Go Back
Golden baked chicken tzatziki casserole with fresh herbs and melted cheese.

Dump-and-Bake Chicken Tzatziki Casserole Recipe | Easy Mediterranean Comfort Food

Make this dump-and-bake chicken tzatziki casserole for a quick and flavorful dinner. Tender chicken, creamy tzatziki, fresh veggies, and melted cheese baked together — an easy Mediterranean-inspired comfort food recipe.
Prep Time 15 minutes
Cook Time 45 minutes
Total Time 1 hour
Course Main Dish
Cuisine Comfort Food, Fusion, Mediterranean-inspired
Servings 8
Calories 420 kcal

Equipment

  • 9x13-inch baking dish
  • Mixing bowls
  • Measuring cups & spoons
  • Cutting board & knife
  • Wooden spoon/spatula
  • Aluminum foil

Ingredients
  

  • 2 lbs boneless chicken thighs or breasts, cut into chunks
  • 2 cups rice, pasta, or quinoa (uncooked)
  • 2 cups mixed vegetables (zucchini, peppers, spinach)
  • 2 cups tzatziki sauce (store-bought or homemade)
  • 1 tsp oregano
  • ½ tsp paprika
  • Salt & pepper to taste
  • 1 cup crumbled feta or shredded mozzarella
  • 2 tbsp olive oil
  • Fresh dill or parsley, for garnish

Instructions
 

  • Prep: Preheat oven to 375°F (190°C). Grease baking dish.
  • Layer: Add chicken, rice/pasta, vegetables, and tzatziki sauce. Season with oregano, paprika, salt, and pepper.
  • Top: Sprinkle cheese and herbs over the mixture.
  • Bake: Cover with foil and bake 20 minutes. Remove foil and bake another 20–25 minutes until chicken is cooked through and rice/pasta tender.
  • Serve: Garnish with fresh dill or parsley. Serve hot with lemon wedges.
  • Pro Tip: Cover with foil during the first half of baking to prevent drying.

Notes

  • Make-ahead: Assemble up to 24 hours in advance; refrigerate until ready to bake.
  • Storage: Refrigerate up to 3 days; freeze (without cucumber in tzatziki) up to 1 month.
  • Variations: Swap rice for cauliflower rice (low-carb), add chili flakes for spice, or substitute chickpeas for chicken in vegan versions.
  • Meal prep: Double the recipe and portion into containers for easy lunches.
 
Keyword Chicken tzatziki casserole, dump-and-bake dinner, easy weeknight casserole, Greek-inspired bake, Mediterranean comfort food