Cheesy Chicken Alfredo Lasagna Rolls – Creamy, Comforting & Crowd-Pleasing

Why You’ll Love This Recipe

Welcome to one of my favorite comfort food creations — Cheesy Chicken Alfredo Lasagna Rolls. I first made this dish on a chilly Sunday evening when I had leftover rotisserie chicken and a craving for something creamy and satisfying. It quickly became a family favorite, requested often and devoured every time.

What makes this dish special is its perfect balance of indulgence and practicality. Each roll is packed with tender chicken, rich homemade Alfredo sauce, and gooey melted cheese, all wrapped in a soft lasagna noodle. It’s creamy, cheesy, and totally family-friendly — a guaranteed crowd-pleaser.

Using rotisserie chicken saves time without sacrificing flavor, and the Alfredo sauce is simple yet luxurious. Whether you’re cooking for a weeknight dinner, prepping meals ahead, or feeding a hungry crowd, these lasagna rolls deliver comfort in every bite.

Recipe Summary

Cheesy Chicken Alfredo Lasagna Rolls are a delicious twist on classic lasagna. Instead of layering, you roll up tender noodles filled with shredded chicken, creamy Alfredo sauce, and mozzarella, then bake until bubbly and golden. It’s a dish that feels fancy but is incredibly easy to make.

Perfect for weeknight dinners, meal prep, or freezer meals, these rolls reheat beautifully and can be made ahead for busy days. The homemade Alfredo sauce adds richness, while rotisserie chicken keeps things quick and flavorful. Serve with a side salad or garlic bread for a complete meal that’s comforting and satisfying.

Equipment Needed

To make this dish, you’ll need:

• 9×13 baking dish
• Medium saucepan (for Alfredo sauce)
• Mixing bowls
• Whisk
• Cheese grater
• Slotted spoon or spatula (for assembling and serving)

Ingredients List

For the Alfredo Sauce

• 2 tbsp butter
• 1½ cups heavy cream
• 2 cloves garlic, minced
• ½ tsp garlic powder
• ½ tsp Italian seasoning
• Salt and pepper to taste
• Pinch of nutmeg
• Pinch of red pepper flakes (optional)
• ¾ cup freshly grated Parmesan cheese

For the Lasagna Rolls

• 9 lasagna noodles, cooked and drained
• 1½ cups ricotta cheese
• 1 large egg
• 1½ cups shredded mozzarella cheese
• 2 cups cooked chicken (rotisserie or grilled), shredded
• 2 tbsp chopped fresh parsley

Step-by-Step Instructions

Step 1: Boil and Prep Noodles Cook lasagna noodles according to package instructions until al dente. Drain and lay flat on parchment paper or a clean surface to prevent sticking.

Step 2: Make Alfredo Sauce from Scratch In a medium saucepan, melt butter over medium heat. Add minced garlic and sauté until fragrant. Stir in heavy cream, garlic powder, Italian seasoning, salt, pepper, nutmeg, and red pepper flakes. Simmer gently for 5–7 minutes until slightly thickened. Stir in Parmesan cheese until melted and smooth. Remove from heat.

Step 3: Mix the Filling In a mixing bowl, combine ricotta cheese, egg, 1 cup mozzarella, shredded chicken, and parsley. Season with salt and pepper. Mix until well blended.

Step 4: Assemble the Rolls Spread a thin layer of Alfredo sauce in the bottom of a 9×13 baking dish. Spoon 2–3 tablespoons of filling onto each lasagna noodle and spread evenly. Roll up tightly and place seam-side down in the dish.

Step 5: Layer and Bake Pour remaining Alfredo sauce over the rolls. Sprinkle with remaining mozzarella and extra Parmesan. Cover with foil and bake at 375°F (190°C) for 20 minutes. Remove foil and bake an additional 5 minutes until bubbly and golden.

Step 6: Serve Let cool slightly before serving. Garnish with extra parsley or cracked pepper.

Tip: Use freshly grated cheese for the best melt and flavor — pre-shredded cheese often contains anti-caking agents that affect texture.

Serving Suggestions

Serve these lasagna rolls with:

• Garlic bread for a crunchy, buttery side
• Caesar salad for freshness and balance
• Steamed broccoli for a simple veggie pairing

Wine Pairing: A glass of Chardonnay complements the creamy sauce, while Pinot Grigio adds a crisp contrast. For non-alcoholic options, try sparkling water with lemon or iced herbal tea.

Calories & Nutrition Info

Each roll contains approximately 350–400 calories, depending on ingredients used. They’re high in protein and calcium, making them both satisfying and nourishing. Gluten-Free Option: Use gluten-free lasagna noodles and ensure all other ingredients are certified GF.

Recipe Notes & Variations

• Protein: Use rotisserie chicken for convenience or leftover grilled chicken for smoky flavor.
• Veggies: Add sautéed spinach, mushrooms, or roasted red peppers to the filling.
• Sauce Swaps: Try pesto, tomato cream sauce, or a spicy arrabbiata for a twist.
• Cheese Options: Swap mozzarella for provolone, fontina, or gouda for different flavor profiles.
• Spicy Kick: Add diced jalapeños or a pinch of cayenne to the filling or sauce.

These variations let you customize the dish to suit your taste, dietary needs, or what’s in your fridge.

Storage & Reheating Tips

• Refrigerate leftovers in an airtight container for up to 4 days.
• Freeze individual rolls on a baking sheet, then transfer to freezer bags. Store for up to 2 months.
• Reheat in the oven at 350°F (175°C) until warmed through. Add a splash of cream or milk to keep them moist.
• Microwave in short bursts, covered, with a spoonful of sauce or cream to prevent drying out.

Make-Ahead Tips

• Assemble the lasagna rolls and refrigerate overnight.
• Bake straight from the fridge — just add 5 extra minutes to the cook time.
• You can also freeze unbaked rolls and bake directly from frozen with an extended bake time.

FAQ Section: People Also Ask

Can I use jarred Alfredo sauce? Yes, but homemade offers richer flavor and better texture. If using store-bought, choose a high-quality brand and consider adding extra Parmesan or garlic.

Can I make this ahead of time? Absolutely. Assemble the rolls and refrigerate or freeze. Bake when ready to serve — perfect for meal prep or entertaining.

What’s the best chicken to use? Rotisserie chicken is ideal for flavor and convenience. Baked or grilled chicken breast also works well.

Can I use other cheeses? Yes! Provolone, fontina, gouda, or even a touch of cream cheese can add depth and creaminess.

How do I keep lasagna rolls from falling apart? Don’t overfill the noodles, and roll them tightly. If needed, secure with toothpicks before baking and remove before serving.