Garlic Butter Shrimp Scampi Lasagna

Why Garlic Butter Shrimp Scampi Lasagna?

Imagine the classic Italian lasagna, layered with tender pasta sheets, creamy cheeses, and savory sauce—now elevate it by blending in the rich, buttery flavors of shrimp scampi. This Garlic Butter Shrimp Scampi Lasagna is a unique fusion that brings the best of both worlds together, offering an indulgent yet approachable dish perfect for any special occasion or cozy dinner at home.

The luscious garlic butter sauce infused with fresh shrimp creates a luxurious seafood twist, while the combination of ricotta, mozzarella, and Parmesan cheeses adds the perfect creamy texture. This recipe promises a symphony of flavors and textures that will impress your family and guests alike.

In this article, you’ll discover the inspiration behind this dish, learn how to prepare the shrimp scampi sauce, master the layering technique, and finish with baking tips for a beautifully golden lasagna. Let’s dive into this delicious journey!

The Inspiration & Flavor Profile

Shrimp scampi and lasagna each have rich culinary histories. Shrimp scampi—originating from Italian-American coastal kitchens—is known for its simple yet bold flavors: garlic, butter, white wine, lemon, and fresh herbs. Lasagna, a classic Italian comfort food, traditionally features layers of pasta, meat or vegetables, cheese, and tomato or béchamel sauce.

Combining these two creates an elegant, sophisticated dish that’s both comforting and refined. The garlic butter sauce provides richness and brightness from lemon and wine, perfectly complementing the tender shrimp. Layering this with creamy ricotta, stretchy mozzarella, and nutty Parmesan cheese creates a delightful textural contrast.

You’ll experience juicy shrimp nestled between silky pasta sheets and gooey melted cheese, with every bite bursting with the fresh flavors of garlic, herbs, and a hint of zest. This lasagna is a celebration of indulgence balanced with fresh, vibrant ingredients.

Key Ingredients & Their Roles

Shrimp: Use peeled and deveined shrimp, fresh or properly thawed frozen. Opt for medium to large shrimp for a satisfying bite. Quality shrimp will deliver the sweetest, most tender texture.

Garlic & Butter: The heart of the scampi sauce. Fresh garlic minced finely releases a fragrant, pungent aroma, while quality unsalted butter adds richness and silkiness to the sauce.

White Wine & Lemon Juice: These ingredients provide essential acidity to balance the butter’s richness. A dry white wine such as Pinot Grigio or Sauvignon Blanc works best. No wine? Substitute with chicken broth and a splash of extra lemon juice.

Lasagna Noodles: Choose traditional boiled noodles or no-boil varieties for convenience. Properly cooked noodles ensure tender layers without sogginess.

Cheeses: Ricotta brings creaminess and subtle sweetness; mozzarella offers gooey stretch and mild flavor; Parmesan adds sharp, nutty depth. Together, they create a rich, layered cheese profile.

Fresh Herbs: Parsley and basil add brightness and freshness, both within the sauce and as garnish.

Additional Seasonings: Salt and pepper enhance overall flavor; red pepper flakes provide a gentle heat if desired.

Olive Oil & Broth: Olive oil is used for sautéing garlic and shrimp; broth helps add moisture and depth to the sauce without heaviness.

Preparing the Garlic Butter Shrimp Scampi

Start by heating olive oil and butter in a large skillet over medium heat. Once melted and sizzling, add the minced garlic and sauté until fragrant—about 30 seconds to 1 minute. Avoid burning the garlic to prevent bitterness.

Add the shrimp to the pan in a single layer. Cook for 1-2 minutes per side until they turn pink and opaque. Be careful not to overcook, as shrimp become rubbery quickly. Remove shrimp and set aside to keep them tender and juicy.

In the same pan, pour in white wine and lemon juice, scraping up any browned bits from the bottom for extra flavor. Let the liquid simmer until slightly reduced, about 2-3 minutes. This reduction concentrates flavors and balances richness.

Return the shrimp to the pan, toss gently to coat in the sauce, and add chopped fresh parsley for brightness. The garlic butter shrimp scampi sauce is now ready to be layered into the lasagna.

Pro Tip: Add shrimp just before assembling your lasagna to keep them plump and tender, avoiding overcooking during baking.

Assembling the Lasagna Layers

Begin by spreading a thin layer of the garlic butter shrimp scampi sauce on the bottom of your baking dish to prevent sticking.

Layer cooked lasagna noodles evenly on top, overlapping slightly but not crowding. Spread a generous layer of ricotta cheese mixed with a pinch of salt and pepper over the noodles.

Next, spoon on some shrimp scampi with its sauce, ensuring an even distribution of shrimp throughout the pan. Sprinkle shredded mozzarella and a light dusting of Parmesan over the sauce.

Repeat these layers—noodles, ricotta, shrimp scampi, mozzarella, Parmesan—until you use all your ingredients, finishing with a final layer of mozzarella and Parmesan on top for a golden crust.

To avoid watery lasagna, drain noodles well if boiling, and keep the scampi sauce slightly thickened by simmering it before layering.

Important: Let your assembled lasagna rest uncovered for 15 minutes after baking to allow it to set. This resting time helps achieve cleaner slices and better texture.

Baking & Finishing Touches

Preheat your oven to 375°F (190°C). Cover the lasagna loosely with foil and bake for about 25-30 minutes to heat through and meld the flavors.

Remove the foil and bake an additional 10-15 minutes to allow the cheese on top to melt fully and turn a beautiful golden brown. For an extra bubbly crust, you can broil for 1-2 minutes but watch carefully to avoid burning.

Once out of the oven, garnish with freshly chopped parsley or basil and a sprinkle of lemon zest for a pop of freshness and color.

Check doneness by ensuring the lasagna is hot and bubbly in the center and the cheese is melted and lightly browned.

FAQs About Garlic Butter Shrimp Scampi Lasagna

Q: Can I use frozen shrimp for this recipe?
A: Yes! Just make sure to fully thaw and pat the shrimp dry to avoid excess water, which can make the lasagna watery. Use peeled and deveined shrimp for best results.

Q: Can I make this recipe gluten-free?
A: Absolutely. Substitute traditional lasagna noodles with gluten-free pasta sheets or use thinly sliced zucchini or eggplant for a low-carb alternative.

Q: What if I don’t have white wine?
A: No problem! Use chicken broth with a splash of extra lemon juice or a touch of white grape juice for acidity.

Q: How can I prevent the lasagna from being watery?
A: Drain noodles thoroughly, simmer the shrimp scampi sauce until slightly thickened, and avoid adding too much liquid during layering.

Q: Can I prepare this dish ahead of time?
A: Yes, assemble the lasagna up to 24 hours in advance, cover tightly, and refrigerate. Bake it straight from the fridge, adding extra baking time as needed.

Q: How do I reheat leftovers?
A: Reheat individual portions in the microwave or reheat the entire dish covered with foil in a 350°F oven until warmed through.

Variations to Customize Your Dish

  • Spicy Kick: Add red pepper flakes to the scampi sauce or sprinkle some cayenne in the cheese layers for a subtle heat that complements the garlic butter.

  • Veggie Boost: Incorporate sautéed spinach, mushrooms, or zucchini slices into the layers for added nutrition and flavor.

  • Creamier Sauce: Stir in a splash of heavy cream or mascarpone cheese to the scampi sauce before layering for an extra rich, velvety texture.

  • Herb Infusion: Experiment with fresh thyme or oregano alongside parsley and basil to elevate the herbal aroma.

  • Cheese Swap: Try swapping mozzarella for provolone or adding a layer of fontina for a nuttier, creamier cheese profile.

  • Shellfish Variety: Substitute shrimp with scallops or chunks of lobster meat for a more decadent seafood lasagna.

Expert Tips for Perfect Garlic Butter Shrimp Scampi Lasagna

  • Don’t Overcook Shrimp: Shrimp cook quickly and continue to cook in the oven. Adding them last keeps them tender.

  • Use Fresh Ingredients: Fresh garlic, fresh herbs, and good-quality butter and cheeses make a noticeable difference.

  • Simmer Sauce to Thicken: Allow the scampi sauce to reduce slightly to avoid soggy layers.

  • Rest After Baking: Let the lasagna rest at least 15 minutes after baking for easier slicing and better flavor melding.

  • Even Layering: Spread each component evenly to ensure balanced flavor in every bite.

  • Use a Sharp Knife: When slicing, use a sharp, serrated knife dipped in hot water and wiped dry for clean cuts.

Serving Suggestions

Garlic Butter Shrimp Scampi Lasagna pairs beautifully with light, crisp side dishes to balance its richness. Consider serving with:

  • A simple mixed greens salad dressed in lemon vinaigrette to echo the brightness in the lasagna.

  • Roasted asparagus or steamed green beans tossed with a little olive oil and sea salt.

  • Garlic bread or crusty baguette for soaking up extra sauce.

  • A chilled glass of white wine like Pinot Grigio or Sauvignon Blanc to complement the garlic butter and shrimp flavors.

For a festive touch, garnish each serving with freshly chopped parsley and a thin lemon wedge on the side.

Storage & Make-Ahead Tips

  • Refrigerate: Store leftovers in an airtight container for up to 3 days.

  • Freeze: Wrap tightly with plastic wrap and aluminum foil, then freeze for up to 2 months. Thaw overnight in the refrigerator before reheating.

  • Reheat: Oven reheating covered with foil helps retain moisture. Microwave reheating is convenient for single servings but may cause uneven warming.

  • Make Ahead: Assemble the lasagna the day before baking. Keep it covered in the fridge, then bake fresh when ready to serve. This makes entertaining stress-free and allows flavors to meld even more.

Garlic Butter Shrimp Scampi Lasagna

A luxurious fusion of classic Italian lasagna and rich garlic butter shrimp scampi, layered with creamy ricotta, melted mozzarella, and Parmesan cheese. This indulgent yet approachable seafood lasagna features tender shrimp bathed in a bright, buttery garlic sauce balanced with white wine and lemon juice. Perfect for a special dinner or celebration, it’s a crowd-pleaser that combines comforting textures and sophisticated flavors.
Prep Time 25 minutes
Cook Time 45 minutes
Total Time 1 hour 10 minutes
Course Dinner, Main Course
Cuisine Italian-American fusion
Servings 8
Calories 450 kcal

Equipment

  • Large skillet or sauté pan
  • Large pot for boiling noodles (if using traditional lasagna noodles)
  • 9x13-inch baking dish
  • Mixing bowls
  • Spoon or spatula
  • Cheese grater
  • Aluminum foil
  • Knife and cutting board

Ingredients
  

  • 1 lb medium-large shrimp, peeled and deveined
  • 4 tbsp unsalted butter
  • 2 tbsp olive oil
  • 4 cloves garlic, minced
  • 1/2 cup dry white wine (or chicken broth with 1 tbsp lemon juice)
  • 2 tbsp fresh lemon juice
  • 12 lasagna noodles (traditional or no-boil)
  • 1 ½ cups ricotta cheese
  • 2 cups shredded mozzarella cheese
  • 1 cup grated Parmesan cheese
  • 1/4 cup fresh parsley, chopped (plus more for garnish)
  • Salt and freshly ground black pepper, to taste
  • Red pepper flakes (optional)
  • 1/2 cup low-sodium chicken broth (optional, for sautéing)

Instructions
 

  • Prepare the shrimp scampi: Heat olive oil and 2 tbsp butter in a large skillet over medium heat. Sauté minced garlic until fragrant (~1 minute). Add shrimp; cook 1-2 minutes per side until pink. Remove shrimp and set aside.
  • Make the sauce: Pour white wine and lemon juice into the skillet. Simmer 2-3 minutes until slightly reduced. Return shrimp to pan, toss to coat, and add parsley. Remove from heat.
  • Cook noodles: Boil lasagna noodles according to package instructions if not using no-boil noodles. Drain and set aside.
  • Preheat oven: Set oven to 375°F (190°C).
  • Assemble lasagna: Spread a thin layer of shrimp scampi sauce in a 9x13 baking dish. Layer noodles, ricotta cheese (seasoned with salt and pepper), shrimp scampi, mozzarella, and Parmesan. Repeat layers, finishing with mozzarella and Parmesan on top.
  • Bake: Cover with foil and bake for 25-30 minutes. Remove foil and bake another 10-15 minutes until cheese is golden and bubbly.
  • Rest and serve: Let rest 15 minutes before slicing. Garnish with fresh parsley and lemon zest.

Notes

  • To keep shrimp tender, add them just before assembling the lasagna instead of cooking them fully during baking.
  • Use fresh garlic and high-quality butter for best flavor.
  • For a gluten-free option, substitute lasagna noodles with gluten-free pasta or thinly sliced vegetables.
  • Letting the lasagna rest after baking helps it set for cleaner slices.
  • Leftovers reheat well in the oven or microwave.
Keyword creamy lasagna recipe, easy seafood dinner, Garlic Butter Sauce, Garlic Butter Shrimp Lasagna, Seafood Lasagna, shrimp lasagna, Shrimp Scampi Lasagna,

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Written by Laura Mariano

Laura Mariano is a food blogger who founded Recipes By Gymonset.com to make cooking easier. Growing up on a farm in Spain, Laura was inspired by exquisite dishes prepared using simple ingredients. Laura Mariano is particularly known for making anyone can cook.

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